Sepsis Management
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Sepsis is a medical emergency. For patients with possible septic shock or a high likelihood for sepsis, antibiotics should be administered immediately, ideally WITHIN ONE HOUR of recognition. The choice of agents should be based on the likely organisms and the likely source of infection based on clinical findings. Appropriate microbiological specimens must be taken to guide antimicrobial therapy. Blood cultures and other appropriate specimens should be obtained prior to administration of antibiotics if possible. Antibiotics recently used in the patient’s care should not be among the choices for empiric therapy.
Please refer to the HSE Inpatient Sepsis Algorithms in use in the hospital. See also the National Clinical Guideline on Sepsis Management for Adults (including maternity) 2021 , the Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021 and International Guidelines for the Management of Septic Shock & Sepsis-Associated Organ Dysfunction in Children (SSCGC) .
Sepsis 6 for Adults (except Maternity)
Image reproduced from the National Clinical Guideline on Sepsis Management for Adults (including maternity) 2021 . Please note there is a separate "Sepsis 6 + 1" protocol for maternity.
Sepsis 6+1 for Maternity
Image reproduced from the National Clinical Guideline on Sepsis Management for Adults (including maternity) 2021 .
Sepsis 6 for Paediatrics
Image reproduced from the International Guidelines for the Management of Septic Shock & Sepsis-Associated Organ Dysfunction in Children (SSCGC) .
References
- RCPI Hospital Antimicrobial Stewardship Working Group 2012. Start Smart then Focus Antibiotic Care Bundle. Reproduced with permission. Available from www.rcpi.ie .
- NCEC National Clinical Guideline No. 26 on Sepsis Management for Adults including Maternity. Available from www.gov.ie/en/collection/c9fa9a-national-clinical-guidelines/
- Evans LE, Rhodes A, Alhazzani W, et al. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2021. Critical Care Medicine: November 2021 - Volume 49 - Issue 11 - p e1063-e1143 doi: 10.1097/CCM.0000000000005337. Available from https://www.sccm.org/SurvivingSepsisCampaign/Guidelines/Adult-Patients .
- HSE National Implementation Plan: International Guidelines for the Management of Septic Shock & Sepsis-Associated Organ Dysfunction in Children (SSCGC). 2021. Available from https://assets.hse.ie/media/documents/ncr/international-guidelines-for-the-management-of-septic-shock-and-sepsis-ass_VoOI3j0.pdf .